|Amillennial in eschatology, James Rosscup notes that "In this very thorough, monumental work on Genesis, the author is conservative and uses the original Hebrew constantly. He considers carefully most major truths of the book and uses the grammatical-historical method. This is one of the most valuable works to have on Genesis. It came out originally in 1942." (Commentaries for Biblical Expositors: An Annotated Bibliography of Selected Works)
Rosscup ranks Leupold's commentary as the fifth best detailed exegetical commentary of all time on the book of Genesis.